Cross-Regulation When Presented on Igs TCR Agonist and Antagonist Exert In Vivo
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چکیده
منابع مشابه
TCR agonist and antagonist exert in vivo cross-regulation when presented on Igs.
Ig-PLP1 and Ig-PLP-LR are chimeric Igs expressing proteolipid protein (PLP)-derived T cell agonist (PLP1) and antagonist (PLP-LR) peptides, respectively. Both chimeras, like free PLP1 and PLP-LR peptides, induce in vivo-specific T cell responses. However, the responses induced by Ig-PLP1 and Ig-PLP-LR were cross-reactive with both PLP1 and PLP-LR peptides, while those induced by free peptides w...
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تاریخ انتشار 1998